加州65提案又添4种新物质

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2013年9月13日，加州65提案又添4种新物质，分别是：三氯乙醛、水合氯醛、1,1,1,2-四氯乙烷、三氯乙酸，这些物质早前在2013年7月已向公众进行咨询。自2013年9月13日生效。具体情况如下：

化学品	CAS号	毒性	提交机制
三氯乙醛	75-87-6	致癌	LC
水合氯醛	302-17-0	致癌	LC
1,1,1,2-四氯乙烷	630-20-6	致癌	LC

官方网址： http://www.oehha.ca.gov/prop65/CRNR_notices/list_changes/091313P65list.html原文如下：
2 S: z; Y  }$ T: t5 O9 yProposition 65
CHEMICALS LISTED EFFECTIVE SEPTEMBER 13, 2013 AS KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER: CHLORAL, CHLORAL HYDRATE, 1,1,1.2-TETRACHLOROETHANE, AND TRICHLOROACETIC ACID [09/13/13]

Follow this link to download the Proposition 65 list dated September 13, 2013.

If you would like to sort the list by CAS number or date, please download the list as an Excel document. You can then sort the list by date, CAS number, or chemical name using MS Excel. The Excel document also includes the listing mechanism for each chemical listing and the safe harbor level, if one has been adopted. A hyperlink is provided for those chemicals for which the basis for listing documentation is available electronically. A hyperlink is provided for those safe harbor levels for which the risk assessment documentation is available electronically.

The Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency is adding chloral (CAS No. 75-87-6), chloral hydrate (CAS No. 302-17-0), 1,1,1,2-tetrachloroethane (CAS No. 630-20-6), and trichloroacetic acid (CAS No. 76-03-9) to the list of chemicals known to the State of California to cause cancer for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 651).  The listing of these four chemicals is effective September 13, 2013.

Health and Safety Code section 25249.8(a) incorporates California Labor Code sections 6382(b)(1) and 6382(d) into Proposition 65.  The law requires that certain substances identified by the International Agency for Research on Cancer (IARC) be listed as known to cause cancer under Proposition 65.  Labor Code section 6382(b)(1) refers to substances identified as human or animal carcinogens by IARC.  Labor Code section 6382(d) refers to chemicals that are within the scope of the federal Hazard Communications Standard.  The Federal Hazard Communications Standard relies on chemical designations made by IARC.  An explanation of the carcinogenicity classifications used by IARC, and theMonographs development and peer review by the international Working Groups of scientific experts convened by IARC, may be found at the following URL:  http://monographs.iarc.fr/ENG/Preamble/CurrentPreamble.pdf (IARC Preamble).

The basis for the listing of chloral, chloral hydrate, 1,1,1,2-tetrachloroethane, and trichloroacetic acid was described in a public notice published in the July 26, 2013, issue of the California Regulatory Notice Register (Register 2013, No. 30-Z).  The title of the notice was “Notice of Intent to List Chemicals by the Labor Code Mechanism.”  The publication of the notice initiated a public comment period that closed on August 26, 2013.  No public comments were received.

A complete, updated Proposition 65 list is published elsewhere in this issue of the California Regulatory Notice Registerand is available on the OEHHA website at http://www.oehha.ca.gov/prop65.html.

Chemical	CAS No.	Toxicological Endpoint	Listing Mechanism2
Chloral	75-87-6	cancer	LC
Chloral hydrate	302-17-0	cancer	LC
1,1,1,2-Tetrachloroethane	630-20-6	cancer	LC
Trichloroacetic acid	76-03-9	cancer	LC